Gene function prediction with knowledge from gene ontology

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چکیده

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Gene function prediction with knowledge from gene ontology

Gene function prediction is an important problem in bioinformatics. Due to the inherent noise existing in the gene expression data, the attempt to improve the prediction accuracy resorting to new classification techniques is limited. With the emergence of Gene Ontology (GO), extra knowledge about the gene products can be extracted from GO and facilitates solving the gene function prediction pro...

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MOTIVATION The human genome project has led to the discovery of many human protein coding genes which were previously unknown. As a large fraction of these are functionally uncharacterized, it is of interest to develop methods for predicting their molecular function from sequence. RESULTS We have developed a method for prediction of protein function for a subset of classes from the Gene Ontol...

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ژورنال

عنوان ژورنال: International Journal of Data Mining and Bioinformatics

سال: 2015

ISSN: 1748-5673,1748-5681

DOI: 10.1504/ijdmb.2015.070840